Maxillomandibular advancement is recommended as an effective treatment option for obstructive sleep apnea, with the best candidates typically younger and with lower body mass index. On average, about 80-85% of individuals who undergo this procedure achieve a marked improvement in their sleep apnea and do not need to use other therapies like positive airway pressure… Read more »
Dr. Kezirian’s Blog
ISSS 2025 Annual Meeting Notes
I just returned from the International Surgical Sleep Society 2025 Annual Meeting in Indianapolis, Indiana. Neurostimulation was definitely on the agenda, as it is the most significant area of new technology applied to the treatment of obstructive sleep apnea. I thought I would devote this post to various approaches and the most recent research findings…
Drug-induced sleep endoscopy (DISE) has demonstrated that some patients may have the epiglottis playing a significant role in contributing to their obstructive sleep apnea, separate from other structures like the tongue or oropharyngeal lateral walls that secondarily cause airway obstruction behind the epiglottis. The VOTE Classification that Winfried Hohenhorst, Nico de Vries, and I developed…
NOTE: I was a paid Nyxoah consultant, reviewing preoperative drug-induced sleep endoscopy videos for their clinical trials. Based on this work, I was a coauthor on the paper reporting results of the DREAM trial. I have written previously about the Genio system from Nyxoah and aura6000 system from Livanova, including an update on their clinical trials…
Hypoglossal nerve stimulation has been a major breakthrough in the treatment of obstructive sleep apnea for patients unable to tolerate positive airway pressure therapy. Inspire Medical Systems had the first technology approved by the US Food and Drug Administration in 2014, and I was the first surgeon in the Western United States to offer this…
The Upper Airway Stimulation system from Inspire Medical Systems has been an important and effective treatment option for many patients with obstructive sleep apnea. Like any procedure or technology, there are potential important risks to consider. In the United States, the Food and Drug Administration (FDA) maintains the publicly-available Manufacturer and User Facility Device Experience… Read more »Anteroposterior and Lateral Epiglottis-Related Obstruction in OSA
Nyxoah Genio: DREAM Study Results and FDA Approval!
Inspire V System now available at UCLA
Respiratory sensing lead risks with the Inspire IV system
Reducing sleepiness with Inspire hypoglossal nerve stimulation: efficacy and adherence are both important
Hypoglossal nerve stimulation with the Inspire Upper Airway Stimulation system has been a major advance in the treatment of obstructive sleep apnea. Most studies examining outcomes – including important research on drug-induced sleep endoscopy and Inspire therapy outcomes where we have played a key role – has focused on how well the system works when… Read more »
Video Post: Surgical evaluation and treatment of OSA and improving outcomes of OSA surgery
We have now released two new videos posted on YouTube and the following UCLA websites: UCLA Sleep Surgery UCLA Head and Neck Surgery Webinars UCLAMDChat Webinars The first video discusses surgical evaluation and treatment of obstructive sleep apnea: The second video shares work in sleep surgery – including research that we have performed…
Over the past couple of years, I have seen more patients coming to me, indicating that they have been “diagnosed” with upper airway resistance syndrome (UARS) by so-called sleep experts. I have to stop myself from shaking my head, not knowing whether I should laugh or cry. The problem has become particularly noticeable over the…
My move to UCLA was based on the opportunity to work with a larger team of sleep medicine providers and researchers, including other surgeons who focused in this area: Ashley Kita, MD and Travis Shiba, MD. We have just posted some videos on our UCLA Sleep Surgery website page explaining what we do as surgeons…
What Is Upper Airway Resistance Syndrome (UARS)?
What is unique about UCLA Sleep Surgery?
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