Dr. Kezirian’s Blog

Hypoglossal nerve stimulation is an important treatment option for patients with moderate to severe obstructive sleep apnea who cannot tolerate positive airway pressure therapy (for example, CPAP). The only currently-FDA-approved technology is Upper Airway Stimulation (Inspire Medical Systems, Golden Valley, MN), but multiple technologies are in human clinical trials or under development. One of these… Read more »

Since its FDA approval in 2014, the Upper Airway Stimulation system from Inspire Medical Systems has dominated the landscape of nerve stimulation in the treatment of obstructive sleep apnea. A number of companies have been involved in development of hypoglossal nerve stimulation technologies, and this month one of those companies (LivaNova) had publication of results… Read more »

I have written previously on this blog about our research highlighting the extremely low quality of published “systematic reviews” and “meta-analyses” in the otolaryngology and sleep surgery literature. We have shown that many studies do not adhere to established, accepted research methods for these studies, creating a dangerous situation where publications that pretend to be… Read more »

I am writing from our 28th Annual Advances in Diagnosis and Treatment of Sleep Apnea and Snoring course in Orlando, Florida. This is our first in-person course since 2019, and it was wonderful to be together. I do think more and more educational events will be offered virtually, as it increases access for people who… Read more »

Continuous positive airway pressure (CPAP) is the first-line treatment for obstructive sleep apnea (OSA) in almost all patients in my practice. There are rare cases where I may order mandibular respositioning devices (aka, oral appliances), but CPAP is the primary option, even in patients who specifically request surgical treatment. CPAP has many advantages over alternatives,… Read more »

Surgery for obstructive sleep apnea often involves surgery of the throat that removes, repositions, and/or tightens tissue. Although the goal is to improve or eliminate the sleep apnea, the risks include the potential to disrupt normal function, especially speech and swallowing. Fortunately, speech changes have always been rare, but changes in swallowing have always been… Read more »

Thanksgiving is a time to reflect on our good fortune and express gratitude with family and friends. What a perfect time to express appreciation to current and former fellows who continue to invigorate me with their enthusiasm, intellect, and curiosity. This September at our International Surgical Sleep Society meeting in Philadelphia, I was delighted to… Read more »

Upper Airway Stimulation (Inspire Medical Systems, Golden Valley, MN, USA) is an excellent treatment option for many patients with moderate to severe obstructive sleep apnea who are unable to tolerate positive airway pressure therapy (for example, CPAP or BPAP) well. There are a number of specific criteria to determine whether a patient is eligible for… Read more »

I just returned from a trip to Philadelphia for the back-to-back meetings of the International Surgical Sleep Society and American Academy of Otolaryngology – Head and Neck Surgery. Coming together in-person with long-time colleagues who are also friends to share experiences and ideas was wonderful. A great deal of the meeting was focused on neurostimulation,… Read more »

Twitter and other social media platforms are tremendous resources for sharing information about sleep disorders. I do not pretend to be a social media expert, so I apologize for my simplistic explanations or mistakes here. Patients and health care providers may rely on information available on the Internet (I know I sometimes do). Hashtags allow… Read more »